NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S215699 | ||||
Product Name: Anti-EEPD1 Rabbit Polyclonal Antibody | ||||
Synonyms: HSPC107 | ||||
UNIPROT ID: Q7L9B9 (Gene Accession – NP_085139 ) | ||||
Background: EEPD1(endonuclease/exonuclease/phosphatase family domain containing 1), also known as HSPC107, is a 569 amino acid protein that contains one HhH domain. A significant decrease in the relative transcriptional level of EEPD1 is induced by long-term heat stress exposure. Conversely, EEPD1 is up-regulated in bovine adipogenic processes related to intramuscular pre-adipocyte differentiation. Encoded by a gene that maps to human chromosome 7p14.2, EEPD1 plays a role in DNA binding and repair. Chromosome 7 makes up about 5% of the human genome and contains 158 million bases encoding more than 1,000 genes. Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome are associated with Chromosome 7. | ||||
Immunogen: Synthetic peptide of human EEPD1 | ||||
Applications: ELISA, WB, IHC | ||||
Recommended Dilutions: IHC: 20-100;WB: 200-1000;ELISA: 5000-10000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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