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EGFR (6H11) Mouse mAb

Anti-EGFR (6H11) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261442

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261442
Product Name:   Anti-EGFR (6H11) Mouse Monoclonal Antibody
Synonyms:   EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
UNIPROT ID:   P00533
Background:    EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
Immunogen:    Purified recombinant human EGFR protein fragments expressed in E.coli.
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    6H11-2D11-G3
MW:    Calculated MW: 134 kDa; Observed MW: 175 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Monkey
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of EGFR (6H11) in HeLa using EGFR antibody.

Western blot analysis of EGFR in A549 and COS7 lysates using EGFR antibody.

Immunoprecipitation analysis of EGFR (6H11) in Hela lysates using EGFR antibody.

Immunocytochemistry analysis of EGFR in MDA-MB-468 cells using EGFR antibody.
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