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EIF4E2 Rabbit pAb

Anti-EIF4E2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S212982

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S212982
Product Name:   Anti-EIF4E2 Rabbit Polyclonal Antibody
Synonyms:   4EHP; IF4e; 4E-LP; h4EHP; EIF4EL3
UNIPROT ID:   O60573 (Gene Accession – BC005392 )
Background:    Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity).
Immunogen:    Fusion protein of human EIF4E2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 212982(EIF4E2 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 212982(Anti-EIF4E2 Antibody) at dilution 1/50.
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