NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225280 | ||||
Product Name: Anti-eIF4G1 Rabbit pAb | ||||
Synonyms: p220 | ||||
UNIPROT ID: Q04637 | ||||
Background: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5′-terminal secondary structure and recruitment of mRNA to the ribosome. | ||||
Immunogen: Peptide sequence around aa.1230~1234 (P-V-S-P-L) derived from Human eIF4G. | ||||
Applications: WB,IHC-P,ICC/IF | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Clone ID: – | ||||
MW: Calculated MW: 175 kDa; Observed MW: 220 kDa | ||||
Isotype: IgG | ||||
Purification: Affinity Chromatography | ||||
Species Reactivity: Human | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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