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EMC10 Rabbit pAb

Anti-EMC10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221647

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221647
Product Name:   Anti-EMC10 Rabbit Polyclonal Antibody
Synonyms:   HSM1; HSS1; C19orf63
UNIPROT ID:   Q5UCC4 (Gene Accession – NP_996261 )
Background:    EMC10, also known as C19orf63, C19orf63 is a 262 amino acid protein that exists as two alternatively isoforms and are encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcà receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
Immunogen:    Synthetic peptide of human EMC10
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221647(EMC10 Antibody) at a dilution of 1/45(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221647(Anti-EMC10 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 221647(Anti-EMC10 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D263336(Anti-EMC10 Antibody) at dilution 1/45.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Jurkat, PC-3 and A549 cell lysates;
Primary antibody: 221647(EMC10 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 40 seconds
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