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ENPP1 Rabbit pAb

Anti-ENPP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221231

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221231
Product Name:   Anti-ENPP1 Rabbit Polyclonal Antibody
Synonyms:   M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1
UNIPROT ID:   P22413 (Gene Accession – NP_006199 )
Background:    This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5′ triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with ‘idiopathic’ infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
Immunogen:    Synthetic peptide of human ENPP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 221231(ENPP1 Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the synthetic peptide and then with 221231(Anti-ENPP1 Antibody) at dilution 1/20.
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