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ENSA Rabbit pAb

Anti-ENSA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218947

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218947
Product Name:   Anti-ENSA Rabbit Polyclonal Antibody
Synonyms:   ARPP-19e
UNIPROT ID:   O43768 (Gene Accession – BC000436 )
Background:    The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen:    Fusion protein of human ENSA
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218947(ENSA Antibody) at a dilution of 1/40(Nucleus or Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218947(Anti-ENSA Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 218947(Anti-ENSA Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D225555(Anti-ENSA Antibody) at dilution 1/40.
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