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EPHB4 Rabbit pAb

Anti-EPHB4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221235

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221235
Product Name:   Anti-EPHB4 Rabbit Polyclonal Antibody
Synonyms:   HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11
UNIPROT ID:   P54760 (Gene Accession – NP_004435 )
Background:    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human EPHB4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Neuroscience, Cardiovascular, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer using 221235(EPHB4 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer is first treated with the synthetic peptide and then with 221235(Anti-EPHB4 Antibody) at dilution 1/60.
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