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ErbB 2 (1C4) Mouse mAb

Anti-ErbB 2 (1C4) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261210

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261210
Product Name:   Anti-ErbB 2 (1C4) Mouse Monoclonal Antibody
Synonyms:   ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
UNIPROT ID:   P04626
Background:    This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.
Immunogen:    Synthetic Peptide of HER2
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    1C4-1H3-1H3
MW:    Calculated MW: 138 kDa; Observed MW: 180 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Tonsil tissue using HER2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody.

Western blot analysis of ErbB 2 (1C4) in Hela, A431, MCF-7 lysates using ErbB 2 (1C4) antibody.
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