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ERVW-1 Rabbit pAb

Anti-ERVW-1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220988

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220988
Product Name:   Anti-ERVW-1 Rabbit Polyclonal Antibody
Synonyms:   ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
UNIPROT ID:   Q9UQF0 (Gene Accession – NP_055405 )
Background:    Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene’s protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta.
Immunogen:    Synthetic peptide of human ERVW-1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 220988(ERVW-1 Antibody) at a dilution of 1/45(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 220988(Anti-ERVW-1 Antibody) at dilution 1/45.
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