NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S221983 | ||
Product Name: Anti-ETV2 Rabbit Polyclonal Antibody | ||
Synonyms: ER71; ETSRP71 | ||
UNIPROT ID: O00321 (Gene Accession – NP_055024 ) | ||
Background: ETS translocation variant 2 (ETV2), also known as ETSRP and ER71, is a 37 kDa transcription factor that is expressed in presumptive vascular progenitor cells. It plays an important role in vascular development by promoting the expansion of hemangioblasts and vascular endothelial cells while inhibiting differentiation into cardiomyocytes. It contains one ETS DNA binding domain (aa 234-314). Within aa 125-231, mouse ETV2 shares 54% and 85% aa sequence identity with human and rat ETV2, respectively. | ||
Immunogen: Synthetic peptide of human ETV2 | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: Oct-50; ELISA: 5000-10000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Epigenetics and Nuclear Signaling, Stem Cells | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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