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EXD2 Rabbit pAb

Anti-EXD2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218888

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218888
Product Name:   Anti-EXD2 Rabbit Polyclonal Antibody
Synonyms:   EXDL2; C14orf114
UNIPROT ID:   Q9NVH0 (Gene Accession – BC001962 )
Background:    Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3′-5′ exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Immunogen:    Fusion protein of human EXD2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 40-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218888(EXD2 Antibody) at a dilution of 1/55(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218888(Anti-EXD2 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 218888(Anti-EXD2 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D225443(Anti-EXD2 Antibody) at dilution 1/55.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse brain tissue and Human cerebrum tissue lysates;
Primary antibody: 218888(EXD2 Antibody) at dilution 1/700;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 3 minutes
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