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F2 Rabbit pAb

Anti-F2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221011

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221011
Product Name:   Anti-F2 Rabbit Polyclonal Antibody
Synonyms:   PT; THPH1; RPRGL2
UNIPROT ID:   P00734 (Gene Accession – NP_000497 )
Background:    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
Immunogen:    Synthetic peptide of human F2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221011(F2 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221011(Anti-F2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 221011(Anti-F2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D262357(Anti-F2 Antibody) at dilution 1/35.
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