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F3 Rabbit pAb

Anti-F3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221027

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221027
Product Name:   Anti-F3 Rabbit Polyclonal Antibody
Synonyms:   TF; TFA; CD142
UNIPROT ID:   P13726 (Gene Accession – NP_001984 )
Background:    This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human F3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-250; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221027(F3 Antibody) at a dilution of 1/60(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221027(Anti-F3 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 221027(Anti-F3 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262373(Anti-F3 Antibody) at dilution 1/60.
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