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F5(Coagulation factor V light chain) Rabbit pAb

Anti-F5(Coagulation factor V light chain) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222001

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222001
Product Name:   Anti-F5(Coagulation factor V light chain) Rabbit Polyclonal Antibody
Synonyms:   FVL; PCCF; THPH2; RPRGL1
UNIPROT ID:   P12259 (Gene Accession – NP_000121 )
Background:    This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.
Immunogen:    Synthetic peptide of human F5(Coagulation factor V light chain)
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 222001(F5(Coagulation factor V light chain) Antibody) at a dilution of 1/20(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 222001(Anti-F5(Anti-Coagulation factor V light chain) Antibody) at dilution 1/20.
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