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FADD Rabbit mAb

Anti-FADD Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262204

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262204
Product Name:   Anti-FADD Rabbit Monoclonal Antibody
Synonyms:   FADD; MORT1; GIG3; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity
UNIPROT ID:   Q13158
Background:    Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Immunogen:    A synthetic peptide of human FADD
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-1A6
MW:    Calculated MW: 23 kDa; Observed MW: 28 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis – Caspase family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of FADD in rat Brain, 3T3 lysates using FADD antibody.
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