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FADD Rabbit mAb

Anti-FADD Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262203

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262203
Product Name:   Anti-FADD Rabbit Monoclonal Antibody
Synonyms:   Mort1/FADD
UNIPROT ID:   Q61160
Background:    Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .
Immunogen:    A synthetic peptide of mouse FADD
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-1K1
MW:    Calculated MW: 23 kDa; Observed MW: 28 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of FADD in SH-SY5Y lysates using FADD antibody

Immunohistochemistry analysis of paraffin-embedded mouse liver using FADD antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.
          Publications