Email: info@neweastbio.com   |  Call: 6109452007

FAK (3D8) Mouse mAb

Anti-FAK (3D8) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261098

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261098
Product Name:   Anti-FAK (3D8) Mouse Monoclonal Antibody
Synonyms:   PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK
UNIPROT ID:   Q05397
Background:    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.
Immunogen:    Purified recombinant human FAK protein fragments expressed in E.coli.
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    3D8-H11-E12
MW:    Calculated MW: 119 kDa; Observed MW: 125 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of FAK (3D8) in Hela using FAK antibody.

Western blot analysis of FAK in COS7, HUVEC, A549 and Hela lysates using FAK antibody.

Immunoprecipitation analysis of FAK (3D8) in Hela lysates using FAK antibody.
          Publications