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FBL Rabbit pAb

Anti-FBL Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211205

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211205
Product Name:   Anti-FBL Rabbit Polyclonal Antibody
Synonyms:   FIB; FLRN; Nop1; RNU3IP1
UNIPROT ID:   P22087 (Gene Accession – BC019260 )
Background:    This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Immunogen:    Fusion protein of human FBL
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 211205(FBL Antibody) at a dilution of 1/70(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 211205(Anti-FBL Antibody) at dilution 1/70.
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