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FGF18 Rabbit pAb

Anti-FGF18 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217440

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217440
Product Name:   Anti-FGF18 Rabbit Polyclonal Antibody
Synonyms:   ZFGF5; FGF-18
UNIPROT ID:   O76093 (Gene Accession – BC006245 )
Background:    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Immunogen:    Fusion protein of human FGF18
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217440(FGF18 Antibody) at a dilution of 1/70(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217440(Anti-FGF18 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 217440(Anti-FGF18 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D222362(Anti-FGF18 Antibody) at dilution 1/70.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: SKOV3 cell lysate;
Primary antibody: 217440(FGF18 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
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