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FGF3 Rabbit pAb

Anti-FGF3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219673

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219673
Product Name:   Anti-FGF3 Rabbit Polyclonal Antibody
Synonyms:   INT2; HBGF-3
UNIPROT ID:   P11487 (Gene Accession – NP_005238 )
Background:    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Immunogen:    Synthetic peptide of human FGF3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219673(FGF3 Antibody) at a dilution of 1/60(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 219673(Anti-FGF3 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 219673(Anti-FGF3 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260124(Anti-FGF3 Antibody) at dilution 1/60.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse fetal brain tissue, Mouse brain tissue lysates;
Primary antibody: 219673(FGF3 Antibody) at dilution 1/1200;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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