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FKBP3 Rabbit pAb

Anti-FKBP3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219418

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219418
Product Name:   Anti-FKBP3 Rabbit Polyclonal Antibody
Synonyms:   FKBP-3; FKBP25; PPIase; FKBP-25
UNIPROT ID:   Q00688 (Gene Accession – BC016288 )
Background:    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Immunogen:    Fusion protein of human FKBP3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 200-300;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219418(FKBP3 Antibody) at a dilution of 1/180(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219418(Anti-FKBP3 Antibody) at dilution 1/180.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 219418(Anti-FKBP3 Antibody) at a dilution of 1/180.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D226836(Anti-FKBP3 Antibody) at dilution 1/180.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human bladder transitional cell carcinoma cancer next level 2-3 tissue, Human bladder transitional cell carcinoma grade 2-3 tissue lysates;
Primary antibody: 219418(FKBP3 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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