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FMR1 Rabbit pAb

Anti-FMR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217455

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217455
Product Name:   Anti-FMR1 Rabbit Polyclonal Antibody
Synonyms:   POF; FMRP; POF1; FRAXA
UNIPROT ID:   Q06787 (Gene Accession – BC038998 )
Background:    The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
Immunogen:    Fusion protein of human FMR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217455(FMR1 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217455(Anti-FMR1 Antibody) at dilution 1/80.
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