NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225011 | ||||||
Product Name: Anti-FOXP3 Rabbit pAb | ||||||
Synonyms: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin | ||||||
UNIPROT ID: Q9BZS1 | ||||||
Background: Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. | ||||||
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430 | ||||||
Applications: WB,IHC-P,ELISA | ||||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Clone ID: – | ||||||
MW: Calculated MW: 47 kDa; Observed MW: 47 kDa | ||||||
Isotype: IgG | ||||||
Purification: Affinity Purified | ||||||
Species Reactivity: Human,Mouse,Rat | ||||||
Conjugation: Unconjugated | ||||||
Modification: Unmodified | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||||
Research Areas: Cell Biology | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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