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CX3CR1 Rabbit pAb

Anti-CX3CR1 Receptor Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225026

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225026
Product Name:   Anti-CX3CR1 Rabbit pAb
Synonyms:   CX3CR1; CMKBRL1; GPR13; CX3C chemokine receptor 1; C-X3-C CKR-1; CX3CR1; Beta chemokine receptor-like 1; CMK-BRL-1; CMK-BRL1; Fractalkine receptor; G-protein coupled receptor 13; V28
UNIPROT ID:   P49238
Background:     CX3C motif chemokine receptor 1 (CX3CR1) is known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13). It is a transmembrane protein of the G protein-coupled receptor 1 (GPCR1) family. The receptor binds the inflammatory chemokine CX3CL1 (also called neurotactin in mice or fractalkine in humans). This endogenous ligand solely binds to CX3CR1 receptor. Interaction of CX3CR1 with CX3CL1 can mediate migration, adhesion and retention of leukocytes, because Fractalkine exists as membrane-anchored protein (mCX3CL1) as well as cleaved soluble molecule (sCX3CL1) due to proteolysis by metalloproteinases (MPPs). The shredded form carries out typical function of conventional chemokines, the chemotaxis, while the membrane-bound protein behaves as adhesion molecule for facilitation of diapedesis.
Immunogen:    Synthesized peptide derived from CX3CR1 at AA range: 120-200
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 40 kDa; Observed MW: 40 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Microbiology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing
Immunohistochemistry analysis of paraffin-embedded rat brain using Fractalkine Receptor antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Western blot analysis of Fractalkine Receptor in U87 lysates using Fractalkine Receptor antibody.
Immunohistochemistry analysis of paraffin-embedded rat brain using Fractalkine Receptor antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Immunohistochemistry analysis of paraffin-embedded rat brain using Fractalkine Receptor antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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