Email: info@neweastbio.com   |  Call: 6109452007

FTO Rabbit pAb

Anti-FTO Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217458

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217458
Product Name:   Anti-FTO Rabbit Polyclonal Antibody
Synonyms:   GDFD; ALKBH9; BMIQ14
UNIPROT ID:   Q9C0B1 (Gene Accession – BC003583 )
Background:    This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass inde,x obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Immunogen:    Fusion protein of human FTO
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 217458(FTO Antibody) at a dilution of 1/80(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 217458(Anti-FTO Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 217458(Anti-FTO Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D222388(Anti-FTO Antibody) at dilution 1/80.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: HepG2 cell lysate;
Primary antibody: 217458(FTO Antibody) at dilution 1/1150;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 90 seconds
          Publications