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FUS Rabbit pAb

Anti-FUS Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217914

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217914
Product Name:   Anti-FUS Rabbit Polyclonal Antibody
Synonyms:   TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2
UNIPROT ID:   P35637 (Gene Accession – BC000402 )
Background:    This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Immunogen:    Fusion protein of human FUS
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 217914(FUS Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 217914(Anti-FUS Antibody) at dilution 1/40.
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