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G6PC1 Rabbit pAb

Anti-G6PC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222283

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222283
Product Name:   Anti-G6PC1 Rabbit Polyclonal Antibody
Synonyms:   G6PC; G6PT; GSD1; GSD1a; G6Pase
UNIPROT ID:   P35575 (Gene Accession – NP_000142 )
Background:    Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
Immunogen:    Synthetic peptide of human G6PC1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 70-350; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Cancer, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 222283(G6PC1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 222283(Anti-G6PC1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 222283(Anti-G6PC1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D264328(Anti-G6PC1 Antibody) at dilution 1/70.
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