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GABARAPL2 Rabbit pAb

Anti-GABARAPL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219188

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219188
Product Name:   Anti-GABARAPL2 Rabbit Polyclonal Antibody
Synonyms:   ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
UNIPROT ID:   P60520 (Gene Accession – BC029601 )
Background:    Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Immunogen:    Fusion protein of human GABARAPL2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 219188(GABARAPL2 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 219188(Anti-GABARAPL2 Antibody) at dilution 1/55.
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