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GADD45A Rabbit pAb

Anti-GADD45A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217464

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217464
Product Name:   Anti-GADD45A Rabbit Polyclonal Antibody
Synonyms:   DDIT1; GADD45
UNIPROT ID:   P24522 (Gene Accession – BC011757 )
Background:    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen:    Fusion protein of human GADD45A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 217464(GADD45A Antibody) at a dilution of 1/30(Nucleus).
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