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GALNT1 Rabbit pAb

Anti-GALNT1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213131

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213131
Product Name:   Anti-GALNT1 Rabbit Polyclonal Antibody
Synonyms:   GALNAC-T1
UNIPROT ID:   Q10472 (Gene Accession – BC047746 )
Background:    This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature.
Immunogen:    Fusion protein of human GALNT1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213131(GALNT1 Antibody) at a dilution of 1/90(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 213131(Anti-GALNT1 Antibody) at dilution 1/90.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 213131(Anti-GALNT1 Antibody) at a dilution of 1/90.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D127031(Anti-GALNT1 Antibody) at dilution 1/90.
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