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GAS6 Rabbit pAb

Anti-GAS6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219814

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219814
Product Name:   Anti-GAS6 Rabbit Polyclonal Antibody
Synonyms:   AXSF, AXLLG
UNIPROT ID:   Q14393 (Gene Accession – NP_000811 )
Background:    This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Immunogen:    Synthetic peptide of human GAS6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-May; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219814(GAS6 Antibody) at a dilution of 1/8(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219814(Anti-GAS6 Antibody) at dilution 1/8.
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