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GBA Rabbit pAb

Anti-GBA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222067

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222067
Product Name:   Anti-GBA Rabbit Polyclonal Antibody
Synonyms:   GCB; GBA1; GLUC
UNIPROT ID:   P04062 (Gene Accession – NP_000148 )
Background:    This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human GBA
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 222067(GBA Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 222067(Anti-GBA Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 222067(Anti-GBA Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D263969(Anti-GBA Antibody) at dilution 1/55.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: 231 cell lysate;
Primary antibody: 222067(GBA Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 3 minutes
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