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GCKR Rabbit pAb

Anti-GCKR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220574

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220574
Product Name:   Anti-GCKR Rabbit Polyclonal Antibody
Synonyms:   GKRP; FGQTL5
UNIPROT ID:   Q14397 (Gene Accession – NP_001477 )
Background:    This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Immunogen:    Synthetic peptide of human GCKR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220574(GCKR Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220574(Anti-GCKR Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220574(Anti-GCKR Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261712(Anti-GCKR Antibody) at dilution 1/15.
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