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GDF15 Rabbit pAb

Anti-GDF15 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216532

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216532
Product Name:   Anti-GDF15 Rabbit Polyclonal Antibody
Synonyms:   PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
UNIPROT ID:   Q99988 (Gene Accession – BC000529 )
Background:    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Immunogen:    Fusion protein of human GDF15
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 150-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216532(GDF15 Antibody) at a dilution of 1/150(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216532(Anti-GDF15 Antibody) at dilution 1/150.
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