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GEMIN4 Rabbit pAb

Anti-GEMIN4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222075

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222075
Product Name:   Anti-GEMIN4 Rabbit Polyclonal Antibody
Synonyms:   p97; HC56; HCAP1; HHRF-1
UNIPROT ID:   P57678 (Gene Accession – NP_056536 )
Background:    The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Immunogen:    Synthetic peptide of human GEMIN4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 222075(GEMIN4 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 222075(Anti-GEMIN4 Antibody) at dilution 1/20.
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