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GFI1B Rabbit pAb

Anti-GFI1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222078

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222078
Product Name:   Anti-GFI1B Rabbit Polyclonal Antibody
Synonyms:   BDPLT17; ZNF163B
UNIPROT ID:   Q5VTD9 (Gene Accession – NP_004179 )
Background:    This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human GFI1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 222078(GFI1B Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 222078(Anti-GFI1B Antibody) at dilution 1/40.
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