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GLRX2 Rabbit pAb

Anti-GLRX2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218951

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218951
Product Name:   Anti-GLRX2 Rabbit Polyclonal Antibody
Synonyms:   GRX2; CGI-133
UNIPROT ID:   Q9NS18 (Gene Accession – BC028113 )
Background:    The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.
Immunogen:    Fusion protein of human GLRX2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 150-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 218951(GLRX2 Antibody) at a dilution of 1/150(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 218951(Anti-GLRX2 Antibody) at dilution 1/150.
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