NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225938 |
Product Name: Anti-Glutamate Receptor 2/3 Rabbit pAb |
Synonyms: GluR K2; GluR K3; GLURB; GLURC; GRIA2; GRIA3 |
UNIPROT ID: P42262/P42263 |
Background: Ion channels activated by glutamate are typically divided into two classes. Those sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). |
Immunogen: A synthesized peptide derived from human GluR2+GluR3 |
Applications: WB,IP |
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Clone ID: – |
MW: Calculated MW: 99 kDa; Observed MW: 99 kDa |
Isotype: IgG |
Purification: Affinity Chromatography |
Species Reactivity: Human,Mouse,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: NeuroscienceyyyyyGlutamate Receptor |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of GluR2+GluR3 in (1) Human fetal brain lysates; (2) mouse brain lysates using Glutamate Receptor 2/3 antibody. |