Email: info@neweastbio.com   |  Call: 6109452007

GM2A Rabbit pAb

Anti-GM2A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218166

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218166
Product Name:   Anti-GM2A Rabbit Polyclonal Antibody
Synonyms:   SAP-3; GM2-AP
UNIPROT ID:   P17900 (Gene Accession – BC009273 )
Background:    This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human GM2A
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 218166(GM2A Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 218166(Anti-GM2A Antibody) at dilution 1/25.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Human 2-3 grade bladder transitional cell carcinoma tissue, Mouse kidney tissue, Hela cell, 293T cell, A375 cell;
Primary antibody: 218166(GM2A Antibody) at dilution 1/250;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 seconds
          Publications