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GPR171 Rabbit pAb

Anti-GPR171 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220585

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220585
Product Name:   Anti-GPR171 Rabbit Polyclonal Antibody
Synonyms:   H963
UNIPROT ID:   O14626 (Gene Accession – NP_037440 )
Background:    Probable G-protein coupled receptor 171 (GPR171) is a protein that in humans is encoded by the GPR171 gene. One of the most abundant peptides in brain, LENSSPQAPARRLLPP (named BigLEN), which can activate GPR171. Additional studies showed that the BigLENμgPR171 system plays an important role in regulating feeding and metabolism in mice. Thus, GPR171 is a potential target for developing antiobesity drugs.
Immunogen:    Synthetic peptide of human GPR171
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220585(GPR171 Antibody) at a dilution of 1/40(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220585(Anti-GPR171 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220585(Anti-GPR171 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D261725(Anti-GPR171 Antibody) at dilution 1/40.
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