NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S220588 | ||||
Product Name: Anti-GPR65 Rabbit Polyclonal Antibody | ||||
Synonyms: TDAG8; hTDAG8 | ||||
UNIPROT ID: Q8IYL9 (Gene Accession – NP_003599 ) | ||||
Background: TDAG8 (for T-cell death-associated gene 8) is a seven transmembrane G protein-coupled receptor (GPCR) that was originally identified from a human thyroid cDNA library and subsequently shown to be expressed predominantly in thymus, lymph nodes, peripheral blood leukocytes and spleen. TDAG8, which is alternatively designated GPCR25, is grouped collectively with other GPCRs that are induced during T cell receptor engagement-mediated apoptosis and T cell activation, which also include G2A (for G2 accumulation) and P2Y2 (for P2 nucleotide) receptor. | ||||
Immunogen: Synthetic peptide of human GPR65 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 50-200; ELISA: 2000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction, Cancer | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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