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GPSM2 Rabbit pAb

Anti-GPSM2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222141

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222141
Product Name:   Anti-GPSM2 Rabbit Polyclonal Antibody
Synonyms:   LGN; CMCS; PINS; DFNB82
UNIPROT ID:   P81274 (Gene Accession – NP_037428 )
Background:    The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human GPSM2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 222141(GPSM2 Antibody) at a dilution of 1/65(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 222141(Anti-GPSM2 Antibody) at dilution 1/65.
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