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GRM5 Rabbit pAb

Anti-GRM5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221277

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221277
Product Name:   Anti-GRM5 Rabbit Polyclonal Antibody
Synonyms:   mGlu5; GPRC1E; MGLUR5; PPP1R86
UNIPROT ID:   P41594 (Gene Accession – NP_000833 )
Background:    This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human GRM5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction,Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221277(GRM5 Antibody) at a dilution of 1/60(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221277(Anti-GRM5 Antibody) at dilution 1/60.
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