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GSPT1 Rabbit pAb

Anti-GSPT1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221978

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221978
Product Name:   Anti-GSPT1 Rabbit Polyclonal Antibody
Synonyms:   GST1; ETF3A; eRF3a; 551G9.2
UNIPROT ID:   P15170 (Gene Accession – NP_001123478 )
Background:    Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Immunogen:    Synthetic peptide of human GSPT1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 221978(GSPT1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 221978(Anti-GSPT1 Antibody) at dilution 1/20.
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