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GZMH Rabbit pAb

Anti-GZMH Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221349

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221349
Product Name:   Anti-GZMH Rabbit Polyclonal Antibody
Synonyms:   CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2
UNIPROT ID:   P20718 (Gene Accession – NP_219491 )
Background:    This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]
Immunogen:    Synthetic peptide of human GZMH
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer using 221349(GZMH Antibody) at a dilution of 1/75(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer is first treated with the synthetic peptide and then with 221349(Anti-GZMH Antibody) at dilution 1/75.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Hela and 231 cell lysates;
Primary antibody: 221349(GZMH Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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