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HAVCR2 Rabbit pAb

Anti-HAVCR2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221816

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221816
Product Name:   Anti-HAVCR2 Rabbit Polyclonal Antibody
Synonyms:   TIM3; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
UNIPROT ID:   Q8TDQ0 (Gene Accession – NP_116171 )
Background:    The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Immunogen:    Synthetic peptide of human HAVCR2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 221816(HAVCR2 Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 221816(Anti-HAVCR2 Antibody) at dilution 1/20.
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