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HCN2 Rabbit pAb

Anti-HCN2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219845

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219845
Product Name:   Anti-HCN2 Rabbit Polyclonal Antibody
Synonyms:   BCNG2, HAC-1, BCNG-2
UNIPROT ID:   Q9UL51 (Gene Accession – NP_001185 )
Background:    Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Immunogen:    Synthetic peptide of human HCN2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219845(HCN2 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219845(Anti-HCN2 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 219845(Anti-HCN2 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D260475(Anti-HCN2 Antibody) at dilution 1/80.
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