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HDAC2 Rabbit mAb

Anti-HDAC2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262318

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262318
Product Name:   Anti-HDAC2 Rabbit Monoclonal Antibody
Synonyms:   HDAC2; Histone deacetylase 2; HD2
UNIPROT ID:   Q92769
Background:    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
Immunogen:    Recombinant protein of human HDAC2
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-4E4
MW:    Calculated MW: 55 kDa; Observed MW: 60 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    EpigeneticsyyyyyHistone Acetylation
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of HDAC2(green) in Hela using HDAC2 antibody,and DAPI(blue)

Western blot analysis of HDAC2 in K562, C6, 3T3 lysates using HDAC2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HDAC2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications