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HDAC2 Rabbit pAb

Anti-HDAC2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219850

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219850
Product Name:   Anti-HDAC2 Rabbit Polyclonal Antibody
Synonyms:   HD2, RPD3, YAF1
UNIPROT ID:   Q92769 (Gene Accession – NP_001518 )
Background:    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human HDAC2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cardiovascular, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 219850(HDAC2 Antibody) at a dilution of 1/25(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 219850(Anti-HDAC2 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 219850(Anti-HDAC2 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D260480(Anti-HDAC2 Antibody) at dilution 1/25.
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